Legend T2 & FLAIR images demonstrate a target appearance of alternating areas of high and low signal in the left frontal white matter.

Legend FLAIR & T2W images reveal involvement of the corpus callosum and a second lesion in right periventricular white matter.

Legend T1W image (left) again shows the target lesion. Right images show heterogeneous enhancement. Key words: mri ms multiple sclerosis inflammation demyelinating

Brain Diagnosis: Balo's concentric sclerosis