Legend Coronal T1-WI demonstrates a hypointense lesion centered in the left frontal periventricular white matter. Axial FLAIR sequences demonstrate the characteristic finger-like to ovoid projections of hyperintense signal extending outward from the periventricular white matter.

Legend Axial T2-WI also demonstrates involvement of the brainstem. Notice the bilateral hyperintense lesions along the 5th nerves in the pons.

Legend Sagittal T1-WI demonstrate "Dawson's fingers" (ovoid lesions with their long axis perpendicular to the ventricular surface). Note the classic location with involvement of the corpus callosum. Post-gadolinium T1-WI demonstrates enhancement at the periphery of the left periatrial lesion. Key words: mri ms inflammation demyelinating

Brain Diagnosis: Multiple sclerosis