Legend Axial T2 and FLAIR images show high signal in the frontal and parietal white matter. The abnormal signal extends across the corpus callosum (right).

Legend Axial T2 and FLAIR images demonstrate T2 prolongation in the sub cortical white matter (bilateral temporal and parietal lobes and the left frontal lobe) as well as high signal in the left pons.

Legend Precontrast coronal T1 (top) and post contrast axial T1 weighted MRI shows hypointensity in affected white matter without enhancement. Key words: mri AIDS infection inflammation

Brain Diagnosis: AIDS - Progressive multifocal leukoencephalopathy (PML)