Legend Axial T2 (left) and Coronal T1 (right) images show bilateral basal ganglia, left frontal subcortical white matter, and left corona radiata lesions. The lesions are T2 hyperintense, and show both hyper- and hypointense regions on T1. No significant mass effect is present. Generalized cerebral volume loss is present.

Legend Single Voxel MR Spectroscopy was obtained at the level of the left basal ganglia (voxel 1), and uninvolved occipital lobes (voxel 2). The occipital voxel shows a normal MR spectrum. The voxel centered on the involved left basal ganglia shows a non-neoplastic spectrum with a normal choline/creatine ratio. There is a broad metabolite peak, which incorporates the NAA peak (at 2.0-3.0 ppm), suggesting elevated Glx, acetate, and succinate. Key words: mri mrs infection inflammation fungal fungus

Brain Diagnosis: AIDS - Cryptococcosis