Legend FLAIR axial images reveal severe high signal abnormality in the periventricular white matter.

Legend Sagittal FLAIR scans (left) reveal involvement of the inner fibers of the corpus callosum along the callosal-septal interface (top image) and extension of many of the lesions laterally within the corpus callosum along the ependymal surface (bottom image). On an axial T1WI (right) the lesions are distinctly hypointense with well-defined margins.

Legend Many of these lesions reveal enhancement on post-gad images. Note the curvilinear enhancement of the subcortical U-fibers in the medial right frontal lobe (left image). Key words: mri white matter disease demyelinating

Brain Diagnosis: Acute relapse of multiple sclerosis