The unmyelinated lobar white matter presents low signal on the 3 consecutive axial T1WIs and
high signal on the T2WI (upper right), which is normal for the age. Myelination is present
in the brain stem, and cerebellum and has progressed to the level of the corona radiata.
Spectroscopy. Upper right -basal ganglia with long TE - there is increased Choline/creatine
ratio and decreased NAA/creatine ratio compared to adults. Lower right - basal ganglia with
short TE shows increased Choline/creatine and decreased NAA/creatine compared to adults.
Lower left - Parieto-occipital gray matter with short TE shows increased myo-Inositol/creatine
and Choline/creatine and decreased NAA/creatine compared to adults.
Key words: mrs mri myelination metabolic developmental white matter
Normal 36-week infant MRI & MRS