Gray Matter Heterotopias

Interruption of normal migration of neural blast from the general matrix to the cortex.

Various degrees range from simple nodular gray matter heterotopias to band heterotopias to schizencephaly to lissencephaly and to polymicrogyria.

Seizures, mental retardation.

Association with corpus callosum agenesis, Chiari malformations, Tuberous Sclerosis, septooptic dysplasia.

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