Neurons reach the cortex but are abnormally distributed into multiple small gyri like dimples on the surface of a basketball. The cortex of polymicrogyria have bumps of about 5-7 millimeters in size whereas those of pachygyria are over 8 millimeters in size.

Clinically less severe than lissencephaly. Seizures, developmental delays.

Focal polymicrogyria may be seen with an anomalous draining vein and gliosis.

May be associated with Chiari II, schizencephaly, and congenital infections (C.M.V.).

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