Retinoblastoma

      Retinoblastoma is the most common intraocular malignant tumor of childhood. The disease presents during the first two years of life. Only 10% of cases are inherited as an autosomal dominant trait; the rest result from sporadic mutations of chromosome 13. About 30% are bilateral. On CT scan, they appear as high-density areas arising from the retina. Calcifications are common and, when present in a child, should suggest retinoblastoma. Retinal detachment is invariably present, and the subretinal fluid can be readily identified on MR images. Retinoblastoma must be distinguished from benign causes of leukocoria. Endnote  

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